He have lower back pain for several years, stiff and pain at night, he can bent back normally.

She have lower back pain for 6 years and did some treatments, such as physiotherapy, chiropractor, acupuncture, and massage, with no effect. I suggest she take ibuprofen, she feels much better, and the pain relieves a lot.

Ankylosing spondylitis’s symptoms
(1) pain and discomfort in the waist and/or spine, groin, and buttocks. symptoms lasting ≥ 6 weeks.
(2) pain at night and/or stiffness in the morning.
(3) Relief after the movement.
(4) Heel pain and/or other pain in the points which connect tendon and bone.
(5) Current or previous history of iridocyclitis (redness and swelling).
(6) Family history of ankylosing spondylitis or HLA-B27 positive.
(7) Non-steroidal anti-inflammatory drugs (NSAIDs) can quickly relieve symptoms, such as aspirin, ibuprofen and so on.
(8) Family history, refers to the first or second-generation relatives suffering from ankylosing spondylitis/psoriasis/ulcerative colitis.
(9) C-reactive protein is increased.
(10) inflammation in finger’s joint (toe).

If one patient has four of over ten symptoms, we will think about the suspected Ankylosing spondylitis. Then suggest who will have some CT or MRI and blood tests for the final diagnosis of AS.